The association of serum chemerin levels with retinopathy in patients with type 2 diabetes mellitus: Serum chemerin levels in diabetic retinopathy

Mustafa  Duran; Alpaslan Karabulut; Tayfun  Şahin

doi:10.5281/zenodo.8210180

Authors

Mustafa Duran Hitit University Faculty of Medicine Department of Ophthalmology, Çorum, Turkey https://orcid.org/0000-0002-3178-2880
Alpaslan Karabulut Hitit University Faculty of Medicine Department of Internal Medicine, Çorum, Turkey https://orcid.org/0000-0003-2893-692X
Tayfun Şahin Hitit University Faculty of Medicine Department of Ophthalmology, Çorum, Turkey https://orcid.org/0000-0003-2319-0807

DOI:

https://doi.org/10.5281/zenodo.8210180

Keywords:

Chemerin, diabetic retinopathy, type 2 diabetes mellitus

Abstract

Objective: The aim of this study is to investigate serum chemerin levels in patients with Type 2 diabetes mellitus (T2DM).

Methods: The present study included 57 patients with T2DM and 20 healthy individuals. The T2DM patients were divided into 3 groups including non-retinopathy, non-proliferative retinopathy and proliferative retinopathy. Body Mass Index, HbA1c, fasting blood glucose, central macular thickness of the participants were recorded.

Results: There was not any significant difference between chemerin levels of the patients and the control group (0.93±1.27 µg/ml vs. 1.27±1.11 µg/ml; p=0.08). No significant difference was detected between the patients with retinopathy and the control group for chemerin levels (p=0.13).

Conclusion: The present study detected that there was not any significant difference between T2DM patients and the control group for serum chemerin levels. The reason for that may be due to the fact that serum chemerin levels are affected many other factors.

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